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Gene-based technologies
The attractiveness of RNAi for use in therapy lies in its sensitivity and sequence specificity. However, concerns have arisen concerning sequence specificity, e.g. because the wrong strand of the RNA complex may direct the response to the wrong target nucleic acids. Moreover, RNA complexes of a certain size induce a non-specific interferon dependent...
Published: 10/8/2024
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Inventor(s): Jesper Wengel, Candy Rock, Datum Base
Keywords(s): Battery, Cancer, Diagnostics, Plant Varieties, Technologies, Therapeutics
Category(s): Technology Classifications > Biomedical, Technology Classifications > Diagnostics, Technology Classifications > Medical & Biotechnology, Technology Classifications > Research Tools, Agriculture
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L/R Middle
Improvements to the Bioavailability of Hydrophobic Drugs
Overview
Hydrophobic agents are widely used in medicine, as well as in industry and agriculture, yet some hydrophobic agents have limited bioavailability by oral delivery. Our method of encapsulating hydrophobic agents uses a set of solvents and solutions to micronize the agent, giving it...
Published: 4/4/2025
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Inventor(s): Shannon Pestka
Keywords(s): Battery
Category(s): Technology Classifications > Diagnostics
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Bioassay for Cell Conditioned Media
A novel hybridoma cell line (RMH359) and its use as a cellular bioassay to determine the bioactivity of cell conditioned media (CCM) as a supplement used to support cell survival and promote growth in culture. This bioassay provides a measure of CCM bioactivity in support of hybridoma cells used in the generation and production of monoclonal antibodies.
Benefits
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Published: 10/8/2024
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Inventor(s): Melissa Acosta, Carlos Adres Medina Viana
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Biotechnology
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Functionalized Paramagnetic Particles
Invention Description Biofilms are attached communities of microorganisms that are inherently resistant to antibiotics and killing from the human immune system. These communities are often associated with indwelling medical devices such as catheters, endotracheal tubes, surgical sutures, hip and knee joint prostheses and dental implants.
However, biofilms...
Published: 10/8/2024
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Inventor(s): Jeffrey Leid, Timmothy Vail, Mark Shirtliff
Keywords(s): Technologies
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Biomedical, Technology Classifications > Health
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Blockmir Technology to Selectively Up Regulate Therapeutic Targets and Neutralise Disease-Associated microRNA Activity
Overview
Mirrx Therapeutics A/S is commercializing innovative ”Blockmir” oligonucleotide technology, a proprietary therapeutic paradigm with potential to (i) enhance the protein expression of previously undruggable targets, and (ii) neutralise pathological microRNA expression via selective blockade of microRNA-based gene regulation.
Blockmir
Blockmir...
Published: 10/8/2024
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Inventor(s): David Bauer, Melissa Acosta
Keywords(s): Biomaterials, Technologies, Therapeutics
Category(s): Technology Classifications > Therapeutics, Agriculture > Abandoned Material, Technology Classifications > Diagnostics
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